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    Home » Recipes » Dinner » Chicken Gyros with Homemade Tzatziki Sauce

    Modified: Apr 30, 2025 · Published: Jan 30, 2024 by Angela G. · This post may contain affiliate links.

    Chicken Gyros with Homemade Tzatziki Sauce

    281 shares
    Jump to Recipe

    Greek pitas are stuffed with marinated and pan-fried or grilled chicken tenderloins, cucumber relish, and homemade tzatziki sauce (or save time and use store-bought). These chicken gyros are made fresh in just 30 minutes with a few time-saving tricks.

    Mediterranean Chicken Gyros with Tzatziki Sauce
    Chicken Gyros with Tzatziki Sauce
    Chicken Gyros with Tzatziki Sauce
    Chicken Gyros with Homemade Tzatziki Sauce
    Mediterranean Chicken Gyros with Tzatziki Sauce
    Chicken Gyros with Tzatziki Sauce
    Chicken Gyros with Tzatziki Sauce
    Chicken Gyros with Homemade Tzatziki Sauce

    Pair these Chicken Gyros with a side of Greek Orzo Salad, a Cranberry Lemoncello Cosmo and Chocolate-Hazelnut Rolls for dessert.

    Skim by Section
    • ★ Why You'll Love this Recipe ★
    • ★ Ingredients You'll Need ★
    • ★ How to Make this Recipe ★
    • ★ Tips & FAQs ★
    • ★ More Mediterranean Recipes ★
    • Chicken Gyros with Homemade Tzatziki Sauce

    ★ Why You'll Love this Recipe ★

    This delicious Greek-style wrap is made fresh in just 30 minutes with a few time-saving tricks.

    These gyros are made with tender and flavorful chicken and a cucumber relish. The relish adds freshness, flavor, and a crunchy texture. The relish is chopped which makes these gyros less messy to eat.

    Amazing Mediterranean Flavor

    Marinated, pan-fried, or grilled chicken tenderloins paired with cucumber relish, are topped with cool and creamy Tzatziki sauce, then wrapped up in a Greek pita.

    You can wrap these in a thin sheet of deli paper or reusable wax paper to make them easy to store and hold while you eat.

    Chicken Gyros with Tzatziki Sauce

    These chicken gyros are served cold so can be made ahead, wrapped up, and taken to work or on a picnic for lunch!

    ★ Ingredients You'll Need ★

    Here's everything you need to make these gyros, including cucumber relish and a homemade tzatziki sauce.

    Chicken Gyros Ingredients

    For the Marinade

    You will need: olive oil, lemon juice, garlic paste, paprika, Greek seasoning blend, sea salt and pepper, onion powder, garlic powder, and red pepper flakes

    For the Gyros

    You will need: chicken tenderloins, avocado oil or other cooking oil of your choice, and Greek pitas (flatbreads)

    For the Tzatziki Sauce

    If you are short on time, you can use store-bought tzatziki sauce; however, it's very easy to just make your own tzatziki sauce, it's just a matter of gathering the ingredients.

    You will need: English cucumber, Greek yogurt (plain), garlic paste, fresh dill, lemon juice, sea salt, and pepper.

    For the Cucumber Relish

    You will need: English cucumber, cherry tomatoes, green bell pepper, red onion sliced, lemon juice, sea salt, and pepper.

    ★ How to Make this Recipe ★

    This recipe comes together in just a few simple steps.

    How to Make Chicken Gyros with Tzatziki Sauce
    1. Mix together marinade ingredients.
    2. Marinate chicken.
    3. Cook chicken on the stove top or grill.
    4. Prepare relish.
    5. Prepare tzatziki sauce or use store-bought.
    6. Assemble gyros.

    How to Make the Tzatziki Sauce

    How to Make Tzatziki Sauce

    Making homemade tzatziki sauce is as simple as stirring all the ingredients together. You will need to grate and squeeze excess moisture from the cucumber before combining the remaining ingredients.

    ★ Tips & FAQs ★

    Do I need to remove the tendon from the chicken tenderloins?

    Removing the tendon from tenderloins is optional. Tendons are edible and are not harmful, however, they are typically removed because they can be rubbery in texture which maybe undesirable. I usually don't worry about removing them and don't notice them once cooked but in case you want to remove them, here's how.
    Here's how to remove the tendon:
    -Place chicken flat on a cutting board.
    -Positioned the tines of a fork around the tip of tendon.
    -Pinch the end of the tendon (I use a paper towel for added grip).
    -Hold the fork while pulling up on the tendon.
    The tendon will slide out of the chicken and can be discarded.
    If you want to avoid this all together, you can opt to use chicken cutlets or sliced chicken breasts instead.

    What's the difference between chicken cutlets and chicken tenderloins?

    They are two different parts of the chicken. Tenderloins are a separate piece of meat than the breast. They are more tender so are a little more desirable in texture have a different flavor. Cutlets are chicken breast, cut in half to thin them out.
    You can use them interchangeably but doing so will slightly affect flavor and texture.

    Can I swap out the chicken with steak for gyros?

    Absolutely! These gyros are amazing with either steak or chicken. Try using sirloin steak, cooked the same way as the chicken (grilled or on the stove top), and then slice into strips or bite-sized pieces before layering into the pitas.

    Storing Leftovers

    Leftovers can be stored by wrapping tightly or storing in an airtight container in the fridge for up to 3 days. No reheating is needed unless you want to remove chicken and warm it a touch.

    These gyros are not freezer-friendly.

    ★ More Mediterranean Recipes ★

    • Cold Cucumber and Tomato Gazpacho Soup
      Gazpacho Soup
    • Mediterranean Turkey Skillet with Feta and Tomatoes
      Mediterranean Turkey Skillet
    • Street Cart Chicken Shawarma Rice Bowl
      Chicken Shawarma Bowl
    • Greek Burger with Tzatziki sauce, Lettuce, Tomato and Red Onion
      Greek Turkey Burgers

    Love Mediterranean flavors?

    Browse all my easy Mediterranean recipes and be sure to Pin your favorites for later!

    Greek Chicken Gyros with Tzatziki Sauce

    Chicken Gyros with Homemade Tzatziki Sauce

    Author: Angela G.
    Greek pitas are stuffed with marinated and pan-fried or grilled chicken tenderloins, cucumber relish, and homemade tzatziki sauce (or save time and use store-bought). These chicken gyros are made fresh in just 30 minutes with a few time-saving tricks.
    5 from 1 review
    Reviews
    Course: Dinner, Lunch
    Cuisine: American, Greek, Mediterranean
    Skill Level: Easy
    Prep Time: 20 minutes minutes
    Cook Time: 10 minutes minutes
    Total Time: 30 minutes minutes
    Servings: 6
    Yield: 6 gyros

    Equipment

    • skillet

    Ingredients 

    Marinade

    • 3 tablespoon olive oil
    • 1 lemon juiced
    • 3 teaspoon garlic paste
    • 1 teaspoon paprika
    • 1 teaspoon Greek seasoning blend
    • 1 teaspoon sea salt and pepper each
    • ½ teaspoon onion powder
    • ½ teaspoon garlic powder
    • ½ teaspoon red pepper flakes  more or less to adjust heat

    Gyros

    • 1 ½ lb chicken tenderloins
    • 1 tablespoon avocado oil
    • 6 Greek pitas (flatbreads) 

    Tzatziki Sauce

    • ½ English cucumber grated and squeezed
    • 1 cup Greek yogurt (plain)
    • 4 teaspoon garlic paste
    • 2 tablespoon fresh dill
    • ½ lemon juiced
    • ¼ teaspoon sea salt
    • ¼ teaspoon black pepper 

    Cucumber Relish

    • ½ English cucumber chopped
    • ¾ cup cherry tomatoes quartered
    • ½ cup green bell pepper chopped
    • ¼ cup red onion sliced
    • ¼ cup parsley finely chopped
    • 1 lemon juiced
    • ¼ teaspoon salt and pepper each
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    Instructions

    • Marinate chicken. In a large bowl, whisk to combine marinade ingredients.
      Add chicken and toss to fully coat, cover, and place in fridge to marinate while preparing sauce and relish.
    • Make Tzatziki sauce. In a medium bowl, combine Tzatziki sauce ingredients, cover, then place in fridge.
    • Make relish. In a medium bowl, add cucumber relish ingredients. Stir until well mixed. Cover and place in fridge.
    • Cook chicken. In a large skillet over, medium heat, add 1 tablespoon of oil. Once oil is hot add chicken. Cook chicken for 4 minutes on each side or until the juices run clear.
      Cook to an internal temperature of 165°F. When done, move to cutting board and cover with foil to let it rest for a few minutes then slice.
    • Assemble pita wraps. Take each pita and evenly distribute chicken, sauce, and cucumber relish. Fold gyro and wrap in deli paper to hold it in place.

    Notes

    • Optional: to remove tendon from tenderloins, see Tips & FAQs section above for instructions.
    • Chicken can be cooked on the grill if preferred. Cook for 3-4 minutes on each side at a temperature of 350ºF or until internal temperature reads 165ºF.

    Nutrition Facts

    Serving: 1gyro | Calories: 429kcal | Carbohydrates: 44g | Protein: 34g | Fat: 13g | Saturated Fat: 2g | Polyunsaturated Fat: 2g | Monounsaturated Fat: 8g | Trans Fat: 0.01g | Cholesterol: 74mg | Sodium: 1036mg | Potassium: 801mg | Fiber: 4g | Sugar: 4g | Vitamin A: 546IU | Vitamin C: 48mg | Calcium: 145mg | Iron: 2mg
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